Evaluating maternal imprinting effects for growth and reproductive traits in Murciano-Granadina goats

Document Type : Original Research Article (Regular Paper)

Authors

1 Department of Agriculture, Minab Higher Education Center, University of Hormozgan, Bandar Abbas, Iran

2 Department of Animal Science, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, Iran

Abstract

This research aimed to conduct a genetic analysis of maternal imprinting effects on growth and reproductive characteristics in the Murciano-Granadina goats. Data for the present study were recorded between 2016 and 2022 on a farm in the Kerman province, Iran. Traits studied were body weight at birth (WB) and weaning (WW), pre-weaning average daily gain (ADG), Kleiber ratio (KR) and growth efficiency (GE). Reproduction traits were litter size at birth (LSB), litter size at weaning (LSW), total litter size at birth (TLWB) and total litter size at weaning (TLWW). An animal model was used to analyze the data. Comparison of the models with and without maternal imprinting effects was performed using Akaike's information criterion (AIC). Maternal imprinting had a significant impact on WB and LSW. The heritability estimates for maternal imprinting ( ) were 0.07±0.07 for WB and 0.07±0.02 for LSW. Accounting for maternal imprinting effects into the model resulted in a reduction of 2% and 56% in the direct heritability of WB and LSW, respectively. In addition, the value of  for WB was reduced by approximately 75%. The results implied that there are maternal imprinting effects on the WB and LSW of Murciano-Granadina goats. Hence, the genetic evaluation models for these traits should consider the effect of maternal imprinting effect.

Keywords

Main Subjects

References

Akaike, H., 1974. A new look at the statistical model identification. IEEE Transactions on Automatic Control 19, 716-723.
Amiri Roudbar, M., Abdollahi-Arpanahi, R., Ayatollahi Mehrgardi, A., Mohammadabadi, M., Taheri Yeganeh, A., Rosa, G.J.M., 2018. Estimation of the variance due to parent-of- Origin effects for productive and reproductive traits in Lori-Bakhtiari sheep. Small Ruminant Research 160, 95-102.
Amiri Roudbar, M., Mohammadabadi, M., Mehrgardi, A.A., Abdollahi-Arpanahi, R., 2017. Estimates of variance components due to parent-of-origin effects for body weight in Iran-Black sheep. Small Ruminant Research 149, 1-5.
Blunk, I., Mayer, M., Hamann, H., Reinsch, N., 2017. A new model for parent-of-origin effect analyses applied to Brown Swiss cattle slaughterhouse data. Animal 11 (7), 1096-1106.
Dass, G., Sing, V.K., Ayub, M., 2004. Growth performance of Magra sheep under hot arid climate. Indian Journal of Animal Science 74, 441-443.
Delgado, J.V., Landi, V., Barba, C.J., Fernandez, J., Gomez, M.M., Camacho, M.E., Martinez, M.A., Navas, F.J., Leon, J.M., 2017. Murciano-granadina goat: a Spanish local breed ready for the challenges of the twenty-first century. Sustainable Goat Production in Adverse Environments 2, 205-219.
Ghafouri-Kesbi, F., Mokhtari, M., Gholizadeh, M., Amiri Roudbar, M., 2022a. Parental imprinting effects on growth traits and Kleiber ratio in sheep. Journal of Agricultural Science 160 (3-4), 260-269.
Ghafouri-Kesbi, F., Zamani, P., Mokhtari, M., 2022b. Relative contribution of Imprinting, X chromosome and Litter effects to phenotypic variation in economic traits of sheep. Journal of Animal Breeding and Genetics 139, 611-622.
Guilmatre, A., Sharp, A.J., 2012. Parent of origin effects. Clinical Genetics 81 (3), 201-209.
Hofmeister, R.J., S. Rubinacci, S., Ribeiro, D.M. Kutalik, Z., Buil, A., Delanea, O., 2022. Parent-of-origin effects in the UK Biobank. Nature Communications 13, 6668.
Holl, J.W., Cassady, J.P., Pomp, D., Johnson, R.K., 2004. A genome scan for quantitative trait loci and imprinted regions affecting reproduction in pigs. Journal of Animal Science 82, 3421-3429.
Hu, Y., Rosa, G.J.M., Gianola, D., 2016. Incorporating parent-of-origin effects in whole-genome prediction of complex traits. Genetic Selection Evolution 48, 34.
Hubert, J.N., Perret, M., Riquet, J., Demars, J., 2024. Livestock species as emerging models for genomic imprinting. Frontier in Cell and Developmental Biology 12, 1348036.
Karami, K., Zerehdaran, S., Javadmanesh, A., Shariati, M.M., 2019. Assessment of maternal and parent of origin effects in genetic variation of economic traits in Iranian native fowl. British Poultry Science 60, 486-492.
Kheirabadi, K., 2024. Quantitative analysis of gametic imprinting effects on productive and reproductive performances of Markhoz goat. Small Ruminant Research 240, 107373.
Kleiber, M., 1947. Body size and metabolic rate. Physiology Reviews 27, 511-541.
Laurin, C., Cuellar-Partida, G., Hemani, G., Smith, G.D., Yang, J., Evans, D.M., 2018. Partitioning phenotypic variance due to parent-of-origin effects using genomic relatedness matrices. Behavior Genetics 48, 67-79.
Lawson, H.A., Cheverud, J.M., Wolf, J.B., 2013. Genomic imprinting and parent-of-origin effects on complex traits. Nature Reviews Genetics 14, 609-17.
Leon, J.M., Macciotta, N.P.P., Gama, L.T., Barba, C., Delgado, J.V., 2012. Characterization of the lactation curve in MurcianoGranadina dairy goats. Small Ruminant Research 107(2-3), 76-84.
Macias-Velasco1, J.F., Pierre, C.L.S., Wayhart, J.P., Yin, L., Spears, L., Miranda, M.A., Carson, C., Funai, K., Cheverud, J.M., Semenkovich, C.F., Lawson, H.A., 2022. Parent-of-origin effects propagate through networks to shape metabolic traits. Evolutionary Biology 1, e72989.
Martinez, S., Franco, I., Carballo, J., 2011. Spanish goat and sheep milk cheese. Small Ruminant Research 101 (1-3), 41-54.
Meyer, K., 2020. WOMBAT: A tool for estimation of genetic parameters highlights and updates. The 6th International Conference on Quantitative genetics, pp. 3-13.
Meyer, K., Tier, B., 2012. Estimates of variances due to parent of origin effects for weights of Australian beef cattle. Animal Production Science 52, 215-224.
Mokhtari, M., Barazandeh, A., Roudbari, Z., Ghafouri-Kesbi, F., Amiri Roudbar, M., 2022a. Quantifying parent-of-origin variation in growth and reproductive traits of Kermani sheep. The Journal of Agricultural Science 160 (5), 391-396.
Mokhtari, M., Barazandeh, A., Roudbari, Z., Bahrampour, J., Ghafouri-Kesbi, F., Amiri Roudbar, M., 2022b. Genetic analysis of parent-of-origin effects on growth traits and yearling greasy fleece weight in Raeini Cashmere goat. Small Ruminant Research 216, 106813.
Mokhtari, M., Esmailizadeh, A., Mirmahmoudi R., Roudbari Z., Barazandeh, A., Gutierrez, JP., Mohebbinejad, E., 2024a. Genetic and phenotypic analysis of reproductive traits in the Murciano-Granadina does: Predictive ability of the statistical models and estimation of genetic parameters. Small Ruminant Research 232, 107221.
Mokhtari, M., Esmailizadeh, A., Roudbari Z., Barazandeh. A., Gutierrez, JP., Mohebbinejad, E., 2024b. Early growth performance in the Murciano-Granadina goats: Insights from genetic and phenotypic analyses. The Journal of Agricultural Science 162 (2), 165-172.
Neugebauer, N., Luther, H., Reinsch, N., 2010. Parent-of- origin effects cause genetic variation in pig performance traits. Animal 4, 672-681.
Okamoto, k., Oishi, K., Nakamura, R., Abe, A., Inoue, K., Kumagai, H., Hirooka H., 2019. Parent‐of‐origin effects on carcass traits in Japanese Black cattle․ Journal of Animal Breeding and Genetics 136 (3), 190-198.
Perdomo-González, D.I., Varona, L., Molina, A., Laseca, N., Valera, M., 2023. Quantitative analysis of parent-of-origin effect in reproductive and morphological selection criteria in the Pura Raza Española horse. Journal of Animal Breeding and Genetics 00, 1-11.
SAS, 2004. SAS User  Guide: Statistics. Version 9.1. SAS Institute Inc., Cary, North Carolina. USA.
Tier, B., Meyer, K., 2012. Analysing quantitative parent-of- origin effects with examples from ultrasonic measures of body composition in Australian beef cattle. Journal of Animal Breeding and Genetics 129, 359-368.
Triantaphyllopoulos, K.A., Ikonomopoulos, I., Bannister, A.J., 2016. Epigenetics and inheritance of phenotype variation in livestock. Epigenetic Chromatin 9 (31), 1-18.
Journal of Livestock Science and Technologies
Volume 12, Issue 2
December 2024
Pages 69-76

Files

Share

How to cite

Statistics