The ameliorative effect of mycosorb in aflatoxin contaminated diet of broiler chickens

Document Type : Research Article (Regular Paper)

Authors

1 Department of Animal Science, Faculty of Agriculture, Bu-Ali Sina University, Hamedan, 6517833131, Iran.

2 Animal Science Department, Veterinary Faculty, Tehran University, Tehran, Iran.

Abstract

This experiment was conducted to study the effect of Aflatoxins (AF) on broiler performance, organ weight, plasma characteristics, protein digestibility, and metabolizable energy of the diets. Dietary treatments were: 1) control diet based on corn and soybean meal; 2, 3 and 4) control diet plus 1 mg kg-1 AF, 1 mg kg-1 AF and 0.25% mycosorb, and 0.25% Mycosorb, respectively. The results in the Aflatoxins and Aflatoxins+ mycosorb treatments showed that dietary AF, significantly decreased the feed intake and weight gain as compared to the control diet (P<0.001). Treatment 2 resulted in inferior feed conversation ratio in comparison to the control diet (p<0.05). Uric acid and total protein in the second and third, and phosphorous only in the third treatment were significantly lower than the control (P<0.05). The in-vivo protein and dry matter digestibility, apparent metabolizable energy (AME) and nitrogen corrected-apparent metabolizable energy (AMEn) were not affected by the treatment (P>0.05). Aflatoxin resulted in the proventriculus enlargement, increased liver weight and AF deposition in the liver and breast muscle (P<0.05). This study clearly demonstrated that Mycosorb was effective in alleviating the adverse effects of dietary aflatoxins in broiler chickens.

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References

  • Abdel-Fattah, S., Abosrea, Y.H., Shehataf, E., Flourage, M.R., Helal, A.D., 2010. The Efficacy of thyme oil as antitoxicant of aflatoxin (s) toxicity in sheep. Journal of Animal Science 6, 948-960.
  • Abdel-Rahman, S.S., Sheble, M.A., Abdel-Azeem, A., Rawi, S.M., 2002. Biochemical and pathological studies on hepatic and renal alterations of male albino rats given aluminum chloride and/or aflatoxin B1. Egyptian Journal of Clinical Pathology 15, 57-73.
  • Abo-Norag, M., Edrington, T.S., Kubena, L.F., Harvey, R.B., Phillips, T.D., 1995. Influence of hydrated sodium calcium aluminosilicate and virginiamycin on aflatoxicosis in broiler chicks. Poultry Science 74, 626–632.
  • Applegate, T.J., Schatzmayr, G., Pricket, K., Troche, C., Jiang, Z., 2009. Effect of aflatoxin culture on intestinal function and nutrient loss in laying hens. Poultry Science 88, 1235–1241.
  • Barabolak, R. J., 1977. Improved procedure for quantitative determination of aflatoxin in corn and wet milled corn products. Journal of the Association of Official Analytical Chemists, 60, 308-310
  • Chen, Y.J., 2003. Mould and mycotoxin: Control from grain to feeding. Feed International. 6th Ed.   December. Volume 24, pp. 22-26.
  • Devegowda, G., Murthy, T.N.K., 2005. Mycotoxins: Their effects in poultry and some practical solutions. In: Diaz, D.E. (Eds.), the Mycotoxin Blue Book. Nottingham University Press, Nottingham, UK, pp. 25–56.
  • Edds, G.T., Bortell, R.A., 1983. Biological effects of aflatoxins: poultry aflatoxin and Aspergillus flavus in corn. In: Bulletin of the Alabama Agricultural Experiment Station. (Eds), U.L. Diener, R.L. Asquit, J.W. Dickens. Alabama, AL., Auburn University, pp. 64–66.
  • Edrington, T.S., Kubena, L.F., Harvey, R.B., Rottinghaus, G.E., 1997. Influence of a superactivated charcoal on the toxic effects of aflatoxin or T-2 toxin in growing broilers. Poultry Science 76, 1205–1211.
  • Fatemi, F., Allameh, A., Dadkhah, A., Forouzandeh, M., Kazemnejad, S., Sharifi, R., 2006. Changes in hepatic cytosolic glutathione S-transferase activity and expression of its class-P during the prenatal and postnatal period in rats treated with aflatoxin B1.  Archives of Toxicology 80, 572-579.
  • Fenton, T. W., & FENTON, M. (1979). An improved procedure for the determination of chromic oxide in feed and feces. Canadian Journal of Animal Science 59, 631-634.
  • Fernandez, A., Verde, M., Gascon, M., Ramos, J., Gomez, J., Luco, D.F., Chavez, G., 1994. Variations of clinical, biochemical parameters of laying hens and broiler chickens fed aflatoxin-containing feed. Avian Pathology 23, 37–47.
  • Harvey, R.B., Kubena, L.F., Ellisalde, M.H., Phillips, T.D., 1993. Efficacy of zeollitic ore compounds on the toxicity of aflatoxin to growing broiler chickens. Avian Disease 37, 67–73.
  • Hoerr, F.J., 1997. Mycotoxicosis. In: Calnek, B.W., Barnes, H.J., Beard, C.W., McDougald, L.R., Saif, Y.M. (Eds.), Diseases of Poultry. Iowa State University Press, Ames, IA. pp. 958–962.
  • Huff, W.E., Doerr, J., 1981. Synergism between aflatoxin and ochratoxin an in broiler chickens. Poultry Science 60, 550-555.
  • Huff, W.E., Kubena, L.F., Harvey, R.B., Corrier, D.E., Mollenhauer, H.H., 1986. Progression of aflatoxicosis in broiler chickens. Poultry Science 65, 1891–1899.
  • Hussein, H.S., Brasel, J.M., 2001. Review: Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167, 101–134.
  • Kececi, T., Oguz, H., Kurtoglu, V., Demet, O., 1998. Effects of polyvinylpolypyrrolidone,
  •       Synthetic zeolite and bentonite on serum biochemical and hematological characters of broiler chickens during aflatoxicosis. British Poultry Science 39, 452–458.
  • Kim, B., Kim, D., Park, R., Kwon, K., Ryu, D., Kim, Y., Kim, N., Jeong, S., Kang, B., Kim, K., 2000. Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1oxidizing cytochrome P450 enzymes. Planta Medica 67, 396–399.
  • Kubena, L.F., Edrington, T.S., Kamps-Holtzapple, C., Harvey, R.B., Elissalde, M.H., Rottinghaus, G.E., 1995. Influence of fumonisin B1, present in Fusarium moniliform culture material, and T-2 toxin on turkey poults. Poultry Science 74, 306–313.
  • Kubena, L.F., Harvey, R.B., Bailey, R.H., Buckley, S.A., Rottinghauso, G.E., 1998.  Effects of hydrated sodium calcium aluminosilicate (T-BindTM) on mycotoxicosis in young broiler chickens. Poultry Science 77, 1502–1509.
  • Kubena, L.F., Harvey, R.B., Phillips, T.D., Clement, B.A., 1993. Effects of hydrated sodium calcium aluminosilicate on aflatoxicosis in broiler chicks. Poultry Science 72, 651–657.
  • Kubena, L.F., Harvey, R.B., Phillips, T.D., Corrier, D.E., Huff, W., 1990. Diminution of aflatoxicosis in growing chickens by the dietary addition of a hydrated, sodium calcium aluminosilicate. Poultry Science 69, 727–735.
  • Ledoux, D.R., Rottinghaus, G.E., Bermudez, A.J., Alanso-Debolt, M., 1999.  Efficacy of hydrated sodium calcium aluminosilicate to ameliorate the toxic effects of aflatoxin in broiler chicks. Poultry Science 78, 204–210.
  • Machin, M., Simoyi, M.F., Blemings, K.P., Klandorf, H., 2004. Increased dietary protein elevates plasma uric acid and is associated with decreased oxidative stress in rapidly-growing broiler. Comparative Biochemistry and Physiology 137, 383-390.
  •  Mckenzit, K.S., Kubenta, L.F., Denvir, A.J., Rogers, T.D., Hitchens, G.D., Bailey, R.H., Harvey, R.B., Buckley, S.A., Philips, T.D., 1998. Aflatoxicosis in turkey poults is prevented by treatment of naturally contaminated corn with ozone generated by electrolysis. Poultry Science 77, 1094–1102.
  • Miazzo, R., Peralta, M.F., Magnoli, C., Salvano, M., Ferrero, S., Chiacchiera, S.M., Carvalho, E.C.Q., Rosa, C.A.R., Dalcero, A., 2005.  Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. Poultry Science 84, 1–8.
  • Miazzo, R., Rosa, C.A.R., Queiroz Carvalho, E.C., De Magnoli, C., Chiacchiera, S.M., Palacio, G., Saenz, M., Kikot, A., Basaldella, E., Dalcero, A., 2000.  Efficacy of synthetic zeolite to reduce the toxicity of aflatoxin in broiler chicks. Poultry Science 79, 1–6.
  • Miller, J.D., 1995. Fungi and mycotoxins in grain implications for stored product research. Journal of Stored Products Research 31, 1–16.
  • National Research Council, 1994. Nutrient Requirements of Poultry. 9th rev. ed. National Academy Press, Washington, DC.
  • Nelson, T.S., Johnson, Z.B., Kirby, L.K., Beasley, J.N., 1982. Digestion of dry matter and amino acids and energy utilization by chicks fed molded corn containing mycotoxins. Poultry Science 61, 584–585.
  • Newkirk, R.W.‚ Classen, H.L., Edney, M. J., 2003. Effects of prepress-solvent extraction on the nutritional value of canola meal for broiler chickens. Animal Feed Science and Technology 104, 111-119.
  • Pasha, T.N., Farooq, M.U., Khattak, F.M., Jabbar, M.A., Khan, A.D., 2006. Effectiveness of sodium bentonite and two commercial products as aflatoxin absorbents in diets for broiler chickens. Animal Feed Science and Technology 71, 624-636.
  • Santurio, J.M., Mallmann, C.A., Rosa, A.P., Appel, G., Heer, A., Dageforde, S., Bottcher, M., 1999. Effect of sodium bentonite on the performance and blood variables of broiler chickens intoxicated with aflatoxin. British Poultry Science 40, 115–119.
  • SAS Institute. 2004. SAS User’s Guide, Version 8. SAS Institute, Inc., Cary, NC.
  • Scholl, P.F., McCoy, L., Kensler, T.W., Groopman, J.D., 2006. Quantitative analysis and chronic dosimetry of the aflatoxin B1 plasma albumin adduct lys-AFB1 in rat by isotope dilution mass spectrometry. Chemical Research in Toxicology 19, 44-49.
  • Surai, P.F., Dvorska, J.E., 2005.  Effects of mycotoxins on antioxidant status and immunity. In The Mycotoxin Blue Book, Diaz, D.E., Ed.; Nottingham University Press: Nottingham, UK, pp. 93–137.
  • Tedesco, D., Steidler, S., Galletti, S., Tameni, M., Sonzogni, O., Ravarotto, L., 2004. Efficacy of silymarin-phospholipid complex in reducing the toxicity of aflatoxin B1 in broiler chicks. Poultry Science 83, 1839–1843.
  • Tung, H.T., Wyatt, R.D., Thaxton, P., Hamilton, P.B., 1975. Concentrations of serum proteins during aflatoxicosis. Toxicology and Applied Pharmacology 34, 320–326.
  • Zhao, J., Shirley, R.B., Dibner, J.D., Uraizee, F., Officer, M., Kitchell, M., Vazquez-Anon, M., Knight, C.D., 2010. Comparison of hydrated sodium calcium aluminosilicate and yeast cell wall on counteracting aflatoxicosis in broiler chicks. Poultry Science 89, 2147–2156.

 

Journal of Livestock Science and Technologies
Volume 6, Issue 1
April 2018
Pages 39-47

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